Lobeglitazone Sulfate

CAS No. 763108-62-9

Lobeglitazone Sulfate( —— )

Catalog No. M34318 CAS No. 763108-62-9

Lobeglitazone Sulfate(CKD-501 Sulfate) is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2 diabetes mellitus (T2DM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 172 Get Quote
5MG 264 Get Quote
10MG 424 Get Quote
25MG 655 Get Quote
50MG 975 Get Quote
100MG 1395 Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Lobeglitazone Sulfate
  • Note
    Research use only, not for human use.
  • Brief Description
    Lobeglitazone Sulfate(CKD-501 Sulfate) is a novel thiazolidinedione with anti-inflammatory activity that inhibits LPS-induced NLRP3 inflammasome activation and hepatic inflammation, and can be used in the study of type 2 diabetes mellitus (T2DM).
  • Description
    Lobeglitazone sulfate is a new type of thiazolidinedione. Lobeglitazone sulfate can be used to prevent type 2 diabetes mellitus (T2DM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    NF-κB
  • Target
    NOD
  • Recptor
    NOD
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    763108-62-9
  • Formula Weight
    578.61
  • Molecular Formula
    C24H26N4O9S2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C1SC(C(=O)N1)CC2=CC=C(OCCN(C=3N=CN=C(OC4=CC=C(OC)C=C4)C3)C)C=C2.O=S(=O)(O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bae J, et al. Lobeglitazone: A Novel Thiazolidinedione for the Management of Type 2 Diabetes Mellitus. Diabetes Metab J. 2021 May;45(3):326-336.
molnova catalog
related products
  • NLRP3-IN-9

    NLRP3-IN-9 is an inhibitor of NLRP3 ATPase and caspase-1. NLRP3-IN-9 acts by irreversibly trapping thiol nucleophiles, which prevents both ATP- and nigericin-triggered pyroptosis of human THP-1 cells in a time- and concentration-dependent manner.

  • ADS032

    ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity,, inhibits the activation of NLRP1 and NLRP3, inhibits Nigericin-induced IL-1β production, and can be used to study respiratory inflammation or infection.

  • NBC19

    NBC19 is a potent inhibitor of NLRP3 inflammasome, inhibits nigericin-induced ASC speck formation in post-differentiated THP1 cells with IC50 of 60 nM.